ASCL2 antibody (C-Term)

Catalog No. ABIN7448422

Product Details anti-ASCL2 Antibody

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-ASH2 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Turkey,Bovine,Dog,Horse,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Tasmanian devil,White-tufted-ear marmoset,African elephant,Small-eared galago,Thirteen-lined ground squirrel,Gray short-tailed opossum,Chinese hamster,Naked mole rat,Little brown bat,Green anole,Crab-eating macaque,Duckbill platypus,Zebra finch,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 575 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ASCL2

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Alternative Name: ASH2 (ASCL2 Products)

Synonyms: ASH2 antibody, HASH2 antibody, MASH2 antibody, bHLHa45 antibody, ASCL2 antibody, 2410083I15Rik antibody, Mash2 antibody, achaete-scute family bHLH transcription factor 2 antibody, ASCL2 antibody, Ascl2 antibody

Background: Background: ASH2 (absent, small, or homeotic discs 2) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. ASH2 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, RBBP5,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX.

Gene ID: 9070

NCBI Accession: NP_004665

UniProt: Q9UBL3

Pathways: Stem Cell Maintenance