Arip4 antibody, D130058C05 antibody, G630026H09Rik antibody, Srisnf2l antibody, ARIP4 antibody, HSPC325 antibody, SRISNF2L antibody, RAD54 like 2 (S. cerevisiae) antibody, RAD54 like 2 antibody, Rad54l2 antibody, RAD54L2 antibody
Background
Background: ARIP4 (androgen-interacting protein 4) was identified in a yeast two-hybrid screen using the human androgen receptor (AR) as bait. It was found to be a member of the SNF2 (sucrose nonfermenting 2) protein family and to have ATPase activity. ARIP4 is able to activate AR-dependent transcription. Targeted inactivation of ARIP4 results in embryonic lethality and reduced growth potential of embryonic fibroblast. These findings indicate an important role in development and proliferation.