SLC45A3 antibody (AA 351-450) (Biotin)

Catalog No. ABIN718198

Product Details anti-SLC45A3 Antibody (Biotin)

Target: SLC45A3 (Solute Carrier Family 45, Member 3 (SLC45A3))

Binding Specificity: AA 351-450

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC45A3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Arabidopsis Thaliana

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCANAP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SLC45A3

Target: SLC45A3 (Solute Carrier Family 45, Member 3 (SLC45A3))

Alternative Name: PCANAP2 (SLC45A3 Products)

Background:

Synonyms: IPCA 2, IPCA 8, IPCA6, PCANAP2, PCANAP6, PCANAP8, Prostate cancer associated gene 2, Prostate cancer associated gene 6, Prostate cancer associated gene 8, Prostate cancer associated protein 2, Prostate cancer associated protein 6, Prostate cancer associated protein 8, Prostate cancer-associated protein 6, Prostein, PRST, S45A3_HUMAN, Slc45a3, Solute carrier family 45 member 3.

Background: PSA, prostate specific antigen, is the classic indicator for transformed pro-state tissue, however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia. Prostein, also designated Prostate cancer-associated protein 6, is a prostate-specific, 553 amino acid transmembrane protein that is upregulated by androgens. It is considered a marker for prostate cells since it is expressed in all prostatic glandular cells as well as in normal and cancerous prostate tissues. Since it is able to elicit a tumor-directed cytotoxic T cell response, Prostein may be used as a target for the development of PSA- and T cell-based therapeutic strategies for prostate cancer.

Gene ID: 85414