SOS1 antibody

Catalog No. ABIN7384167

Product Details anti-SOS1 Antibody

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SOS1 (NP_005624.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1 (SOS1 Products)

Synonyms: GF1 antibody, GGF1 antibody, GINGF antibody, HGF antibody, NS4 antibody, 4430401P03Rik antibody, 9630010N06 antibody, AI449023 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, son of sevenless homolog 1 (Drosophila) antibody, SOS1 antibody, Sos1 antibody

Background: SOS1,GF1,GGF1,GINGF,HGF,NS4,This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.

Molecular Weight:

Observed_MW: 175 kDa/200 kDa

Calculated_MW: 36 kDa/152 kDa

Gene ID: 6654

UniProt: Q07889

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling