EEF1E1 antibody

Catalog No. ABIN7384097

Product Details anti-EEF1E1 Antibody

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: A synthetic peptide of human EEF1E1 (NP_004271.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Alternative Name: EEF1E1 (EEF1E1 Products)

Synonyms: p18 antibody, AIMP3 antibody, P18 antibody, 1110003A02Rik antibody, eukaryotic translation elongation factor 1 epsilon 1 antibody, eukaryotic translation elongation factor 1 epsilon 1 L homeolog antibody, EEF1E1 antibody, eef1e1.L antibody, eef1e1 antibody, Eef1e1 antibody

Background: EEF1E1,AIMP3,P18,This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Molecular Weight:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/19 kDa

Gene ID: 9521

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus