AGXT antibody

Catalog No. ABIN7384024

Product Details anti-AGXT Antibody

Target: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human AGXT

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AGXT

Target: AGXT (Alanine Glyoxylate Aminotransferase (AGXT))

Alternative Name: AGXT (AGXT Products)

Synonyms: AGT antibody, AGT1 antibody, AGXT1 antibody, PH1 antibody, SPAT antibody, SPT antibody, TLH6 antibody, Spat antibody, Agt1 antibody, Agxt1 antibody, agt antibody, agt1 antibody, agxt antibody, agxt1 antibody, spt antibody, agxtl antibody, zgc:91879 antibody, wu:fb57d01 antibody, zgc:65930 antibody, alanine-glyoxylate aminotransferase antibody, serine--pyruvate aminotransferase, mitochondrial antibody, alanine-glyoxylate aminotransferase L homeolog antibody, alanine-glyoxylate aminotransferase a antibody, alanine-glyoxylate aminotransferase b antibody, AGXT antibody, Agxt antibody, LOC607355 antibody, agxt.L antibody, agxta antibody, agxtb antibody

Background: AGT,AGT1,Agxt,AGXT1,Alanine glyoxylate aminotransferase,Alanine glyoxylate aminotransferase3,Alanine--glyoxylate aminotransferase,EC 2.6.1.44,EC 2.6.1.51,Hepatic peroxisomal alanine glyoxylate aminotransferase,Hepatic peroxisomal alanine:glyoxylate aminotransferase,L alanine glyoxylate aminotransferase 1,MS773,PH1,Serine pyruvate aminotransferase,Serine--pyruvate aminotransferase,Serine--pyruvate aminotransferase,mitochondrial,Serine:pyruvate aminotransferase,SPAT,SPT,SPYA,TLH6,Serine-pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.

Molecular Weight: 43 kDa

NCBI Accession: NP_000021

UniProt: P21549

Pathways: Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport