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SARS-CoV-2 Spike antibody (RBD)

Reactivity: SARS Coronavirus-2 (SARS-CoV-2) ELISA, IF Host: Human, Mouse Monoclonal D003 unconjugated
Catalog No. ABIN7383756
  • Target See all SARS-CoV-2 Spike Antibodies
    SARS-CoV-2 Spike
    Binding Specificity
    • 39
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    RBD
    Reactivity
    • 64
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Host
    • 25
    • 24
    • 14
    • 2
    • 2
    • 1
    Human, Mouse
    Clonality
    • 43
    • 12
    • 11
    Monoclonal
    Conjugate
    • 57
    • 5
    • 3
    • 1
    This SARS-CoV-2 Spike antibody is un-conjugated
    Application
    • 47
    • 24
    • 17
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    Specificity
    SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
    Purification
    Antigen affinity purification
    Immunogen
    Recombinant 2019-nCoV Spike/RBD Protein (RBD),PKSR030507
    Clone
    D003
    Isotype
    IgG1
    Top Product
    Discover our top product SARS-CoV-2 Spike Primary Antibody
  • Application Notes
    ELISA: 1:5,000-1:10,000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    0.2 μm filtered solution in PBS
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike Products
    Synonyms
    E2 antibody, E2 glycoprotein precursor antibody, Surface Glycoprotein antibody, S antibody
    Target Type
    Viral Protein
    Background
    Coronavirus s1,coronavirus s2,coronavirus spike,cov spike,ncov RBD,ncov s1,ncov s2,ncov spike,novel coronavirus RBD,novel coronavirus s1,novel coronavirus s2,novel coronavirus spike,RBD,S1,s2,Spike RBD,Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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