LRRN2 antibody (AA 601-713)

Catalog No. ABIN717866

Product Details anti-LRRN2 Antibody

Target: LRRN2 (Leucine Rich Repeat Neuronal 2 (LRRN2))

Binding Specificity: AA 601-713

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRN2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRN5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LRRN2

Target: LRRN2 (Leucine Rich Repeat Neuronal 2 (LRRN2))

Alternative Name: LRRN5 (LRRN2 Products)

Synonyms: GAC1 antibody, LRRN5 antibody, LRANK1 antibody, FIGLER7 antibody, LRRN2 antibody, leucine rich repeat neuronal 2 antibody, LRRN2 antibody, Lrrn2 antibody

Background:

Synonyms: Fibronectin type III immunoglobulin and leucine rich repeat domain 7, FIGLER7, GAC 1, GAC1, Glioma amplied on chromosome 1, Glioma amplied on chromosome 1 protein, Leucine rich and ankyrin repeats 1, Leucine rich repeat neuronal 2, Leucine rich repeat neuronal 5, Leucine rich repeat neuronal protein 2, Leucine rich repeat neuronal protein 5, LRANK 1, LRANK1, LRRN 2, LRRN 5, LRRN2, LRRN2_HUMAN.

Background: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene ID: 10446