GCET2 antibody (AA 31-130)

Catalog No. ABIN717731

Product Details anti-GCET2 Antibody

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Binding Specificity: AA 31-130

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCET2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCET2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GCET2

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Alternative Name: Gcet2 (GCET2 Products)

Synonyms: Gcet antibody, Gcet2 antibody, M17 antibody, M17-L antibody, GCAT2 antibody, GCET2 antibody, HGAL antibody, germinal center associated, signaling and motility antibody, germinal center associated signaling and motility antibody, germinal center-associated, signaling and motility antibody, Gcsam antibody, GCSAM antibody

Background:

Synonyms: HGAL, GCAT2, GCET2, Germinal center-associated signaling and motility protein, Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated lymphoma protein, GCSAM, GAL

Background: Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.

Gene ID: 257144

UniProt: Q8N6F7