WASF1 antibody (C-Term)

Catalog No. ABIN7271345

Product Details anti-WASF1 Antibody

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: WASF1 Rabbit pAb

Sequence: VARAAPVCET VPVHPLPQGE VQGLPPPPPP PPLPPPGIRP SSPVTVTALA HPPSGLHPTP STAPGPHVPL MPPSPPSQVI PASEPKRHPS TLPVISDARS VLLEAIRKGI QLRKVEEQRE QEAKHERIEN DVATILSRRI AVEYSDSEDD SEFDEVDWLE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Alternative Name: WASF1 (WASF1 Products)

Synonyms: scar1 antibody, wave1 antibody, ATRANGAP2 antibody, ATSCAR1 antibody, SCAR1 antibody, T14G11.27 antibody, T14G11_27 antibody, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 antibody, wave antibody, WAVE antibody, WAVE1 antibody, AI195380 antibody, AI838537 antibody, Scar antibody, WAVE-1 antibody, WAS protein family member 1 S homeolog antibody, SCAR family protein antibody, WAS protein family member 1 antibody, WAS protein family, member 1 antibody, wasf1.S antibody, AT2G34150 antibody, wasf1 antibody, WASF1 antibody, Wasf1 antibody

Background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.,WASF1,SCAR1,WAVE,WAVE1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Extracellular Matrix,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,WASF1

Molecular Weight: 61kDa

Gene ID: 8936

UniProt: Q92558

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization