zgc:112329 antibody, ATVPS11 antibody, F5G3.7 antibody, F5G3_7 antibody, vacuolar protein sorting 11 antibody, DDBDRAFT_0204454 antibody, DDBDRAFT_0234135 antibody, DDB_0204454 antibody, DDB_0234135 antibody, end1 antibody, pep5 antibody, hvps11 antibody, rnf108 antibody, 1200011A11Rik antibody, END1 antibody, PEP5 antibody, RNF108 antibody, hVPS11 antibody, VPS11, CORVET/HOPS core subunit antibody, vacuolar protein sorting 11 antibody, vacuolar protein sorting protein 11 antibody, VPS11, CORVET/HOPS core subunit S homeolog antibody, Vacuolar peripheral membrane protein similar to S. cerevisiae PEP5 (YMR231W); C terminus is almost identical to nonallelic CaP19.1278 antibody, 7-fold repeat in clathrin and VPS proteins repeat-containing protein antibody, vacuolar protein sorting-associated protein 11 homolog antibody, VPS11 CORVET/HOPS core subunit antibody, VPS11 antibody, vps11 antibody, MCYG_02909 antibody, vps11.S antibody, LOC100632536 antibody, Vps11 antibody
Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],END1, HLD12, PEP5, RNF108, hVPS11,Signal Transduction,VPS11