UBE4B antibody (AA 130-250)

Catalog No. ABIN7271133

Product Details anti-UBE4B Antibody

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Binding Specificity: AA 130-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4B antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: UBE4B Rabbit pAb

Sequence: EVDENDRREK RSLSDKEPSS GPEVSEEQAL QLVCKIFRVS WKDRDRDVIF LSSLSAQFKQ NPKEVFSDFK DLIGQILMEV LMMSTQTRDE NPFASLTATS QPIAAAARSP DRNLLLNTGS N

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-250 of human UBE4B (NP_006039.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Alternative Name: UBE4B (UBE4B Products)

Synonyms: ufd2a antibody, E4 antibody, HDNB1 antibody, UBOX3 antibody, UFD2 antibody, UFD2A antibody, 4930551I19Rik antibody, 4933406G05Rik antibody, AU014668 antibody, D4Bwg0973e antibody, UFD2a antibody, Ufd2p antibody, mKIAA0684 antibody, ubiquitination factor E4B antibody, putative ubiquitin conjugation factor E4 B antibody, ubiquitin conjugation factor E4 B antibody, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antibody, Ube4b antibody, LINJ_30_1070 antibody, LBRM_30_1130 antibody, Tsp_12732 antibody, Tsp_01624 antibody, ube4b antibody, UBE4B antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],E4,HDNB1,UBOX3,UFD2,UFD2A,UBE4B,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE4B

Molecular Weight: 121kDa/133kDa/146kDa/151kDa

Gene ID: 10277

UniProt: O95155