TPCN2 antibody (AA 11-85)

Catalog No. ABIN7271111

Product Details anti-TPCN2 Antibody

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Binding Specificity: AA 11-85

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: TPCN2 Rabbit pAb

Sequence: LLGGARGGGG DWPAGLTTYR SIQVGPGAAA RWDLCIDQAV VFIEDAIQYR SINHRVDASS MWLYRRYYSN VCQRT

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 11-85 of human TPCN2 (NP_620714.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TPCN2

Target: TPCN2 (Two Pore Segment Channel 2 (TPCN2))

Alternative Name: TPCN2 (TPCN2 Products)

Background: This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.,TPCN2,SHEP10,TPC2,Signal Transduction,Neuroscience,Calcium Signaling,TPCN2

Gene ID: 219931

UniProt: Q8NHX9