TWIST2 antibody (AA 1-70)

Catalog No. ABIN7271109

Product Details anti-TWIST2 Antibody

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Binding Specificity: AA 1-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: TWIST2 Rabbit pAb

Sequence: MEEGSSSPVS PVDSLGTSEE ELERQPKRFG RKRRYSKKSS EDGSPTPGKR GKKGSPSAQS FEELQSQRIL

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TWIST2 (NP_476527.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Alternative Name: TWIST2 (TWIST2 Products)

Synonyms: TWIST2 antibody, DERMO1 antibody, FFDD3 antibody, SETLSS antibody, bHLHa39 antibody, Dermo1 antibody, CDERMO-1 antibody, twist family bHLH transcription factor 2 antibody, twist basic helix-loop-helix transcription factor 2 antibody, TWIST2 antibody, Twist2 antibody

Background: The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.,TWIST2,AMS,BBRSAY,DERMO1,FFDD3,SETLSS,bHLHa39,Epigenetics & Nuclear Signaling,Transcription Factors,Stem Cells,Mesenchymal Stem Cells,TWIST2

Molecular Weight: 18kDa

Gene ID: 117581

UniProt: Q8WVJ9

Pathways: Chromatin Binding