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TNFRSF10B antibody
TNFRSF10B
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Monoclonal
unconjugated
Product Details anti-TNFRSF10B Antibody
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Target
See all TNFRSF10B Antibodies
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Reactivity
All reactivities for TNFRSF10B antibodies
Human
Host
All hosts for TNFRSF10B antibodies
Rabbit
Clonality
All clonalities for TNFRSF10B antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF10B antibodies
This TNFRSF10B antibody is un-conjugated
Application
All applications for TNFRSF10B antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purpose
DR5/TRAILR2/TNFRSF10B Rabbit mAb
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Monoclonal Antibodies
Purification
Affinity purification
Immunogen
A synthesized peptide derived from human DR5/TRAILR2/TNFRSF10B
Isotype
IgG
Top Product
Discover our top product TNFRSF10B Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TNFRSF10B
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Target
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Alternative Name
TNFRSF10B (TNFRSF10B Products )
Synonyms
TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009],CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9,TNFRSF10B,Apoptosis,Cancer,CDs,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Growth factors,Growth factors_TNF,Immunology & Inflammation,NF-kB Signaling Pathway,Signal Transduction,TNFRSF10B
Molecular Weight
40,48kDa
Gene ID
8795
UniProt
O14763
Pathways
p53 Signaling , Apoptosis , Positive Regulation of Endopeptidase Activity
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