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Tuberin antibody

TSC2 Reactivity: Human WB, IP Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7271027
  • Target See all Tuberin (TSC2) Antibodies
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Reactivity
    • 283
    • 186
    • 122
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 375
    • 12
    Rabbit
    Clonality
    • 368
    • 19
    Monoclonal
    Conjugate
    • 136
    • 34
    • 33
    • 31
    • 24
    • 23
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    This Tuberin antibody is un-conjugated
    Application
    • 209
    • 173
    • 122
    • 81
    • 80
    • 60
    • 37
    • 31
    • 20
    • 12
    • 7
    • 7
    • 6
    • 5
    • 2
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    TSC2 Rabbit mAb
    Cross-Reactivity
    Human
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Tuberin.
    Isotype
    IgG
    Top Product
    Discover our top product TSC2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Alternative Name
    TSC2 (TSC2 Products)
    Synonyms
    TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
    Background
    Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],LAM,PPP1R160,TSC4,TSC2,Tuberin,tuberin,AMPK Signaling Pathway,Apoptosis,Autophagy,Autophagy_Regulator,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Epigenetics & Nuclear Signaling,G protein signaling,Immunology & Inflammation,Insulin Receptor Signaling Pathway,MAPK-Erk Signaling Pathway,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Akt downstream targets,Protein phosphorylation,Signal Transduction,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Tumor suppressors,TSC2
    Molecular Weight
    200kDa
    Gene ID
    7249
    UniProt
    P49815
    Pathways
    RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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