TMEM100 antibody (C-Term)

Catalog No. ABIN7270950

Product Details anti-TMEM100 Antibody

Target: TMEM100 (Transmembrane Protein 100 (TMEM100))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM100 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: TMEM100 Rabbit pAb

Sequence: ELSCYRCIIP FAVVVFIAGI VVTAVAYSFN SHGSIISIFG LVVLSSGLFL LASSALCWKV RQRSKKAKRR ESQTALVANQ RSLFA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMEM100

Target: TMEM100 (Transmembrane Protein 100 (TMEM100))

Alternative Name: TMEM100 (TMEM100 Products)

Synonyms: 1810057C19Rik antibody, AV011897 antibody, transmembrane protein 100 antibody, TMEM100 antibody, Tmem100 antibody

Background: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.,TMEM100,TMEM100

Molecular Weight: 14kDa

Gene ID: 55273

UniProt: Q9NV29