Translin antibody (AA 50-150)

Catalog No. ABIN7270923

Product Details anti-Translin Antibody

Target: Translin (TSN)

Binding Specificity: AA 50-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Translin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: TSN Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Translin

Target: Translin (TSN)

Alternative Name: TSN (TSN Products)

Synonyms: tsn antibody, MGC52533 antibody, TSN antibody, CG11761 antibody, Dmel\\CG11761 antibody, TB-RBP antibody, BCLF-1 antibody, C3PO antibody, RCHF1 antibody, REHF-1 antibody, TBRBP antibody, TRSLN antibody, 2610034C24Rik antibody, AU040286 antibody, translin L homeolog antibody, translin antibody, haloacid dehalogenase antibody, Translin antibody, tsn.L antibody, TSN antibody, trsn antibody, MMAH_RS03470 antibody, TAGG_RS05275 antibody, Igag_0962 antibody, MFER_RS03645 antibody, DESMU_RS01315 antibody, ARCVE_RS05265 antibody, MZHIL_RS01310 antibody, Tsn antibody

Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.,BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN,TSN,translin,DNA Damage & Repair,Epigenetics & Nuclear Signaling,TSN

Molecular Weight: 17kDa/26kDa

Gene ID: 7247

UniProt: Q15631