TFB1M antibody (AA 28-346)

Catalog No. ABIN7270889

Product Details anti-TFB1M Antibody

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Binding Specificity: AA 28-346

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFB1M antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: TFB1M Rabbit pAb

Sequence: QAAKQLSQNF LLDLRLTDKI VRKAGNLTNA YVYEVGPGPG GITRSILNAD VAELLVVEKD TRFIPGLQML SDAAPGKLRI VHGDVLTFKV EKAFSESLKR PWEDDPPNVH IIGNLPFSVS TPLIIKWLEN ISCRDGPFVY GRTQMTLTFQ KEVAERLAAN TGSKQRSRLS VMAQYLCNVR HIFTIPGQAF VPKPEVDVGV VHFTPLIQPK IEQPFKLVEK VVQNVFQFRR KYCHRGLRML FPEAQRLEST GRLLELADID PTLRPRQLSI SHFKSLCDVY RKMCDEDPQL FAYNFREELK RRKSKNEEKE EDDAENYRL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-346 of human TFB1M (NP_057104.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TFB1M

Target: TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Alternative Name: TFB1M (TFB1M Products)

Background: The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).,TFB1M,CGI-75,CGI75,mtTFB,mtTFB1,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Mitochondrial markers,Nucleotide metabolism,Molecular processes,TFB1M

Molecular Weight: 39kDa

Gene ID: 51106

UniProt: Q8WVM0