TOP3A antibody (AA 1-100)

Catalog No. ABIN7270854

Product Details anti-TOP3A Antibody

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOP3A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: TOP3A Rabbit pAb

Sequence: MILARNYLDV YPYDHWSDKI LPVYEQGSHF QPSTVEMVDG ETSPPKLLTE ADLIALMEKH GIGTDATHAE HIETIKARMY VGLTPDKRFL PGHLGMGLVE

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOP3A (XP_011522303.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TOP3A

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Alternative Name: TOP3A (TOP3A Products)

Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.,TOP3A,TOP3,ZGRF7,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,Cell Biology & Developmental Biology,Apoptosis,TOP3A

Molecular Weight: 101kDa/109kDa/112kDa

Gene ID: 7156

UniProt: Q13472

Pathways: DNA Damage Repair