PDIA11 antibody, TMX antibody, TXNDC antibody, TXNDC1 antibody, 2810425A04Rik antibody, AI465319 antibody, Txndc1 antibody, thioredoxin related transmembrane protein 1 antibody, thioredoxin-related transmembrane protein 1 antibody, TMX1 antibody, Tmx1 antibody
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.,TMX1,PDIA11,TMX,TXNDC,TXNDC1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,TMX1