TXNDC12 antibody (AA 93-172)

Catalog No. ABIN7270800

Product Details anti-TXNDC12 Antibody

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Binding Specificity: AA 93-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: TXNDC12 Rabbit pAb

Sequence: NLEDEEEPKD EDFSPDGGYI PRILFLDPSG KVHPEIINEN GNPSYKYFYV SAEQVVQGMK EAQERLTGDA FRKKHLEDEL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 93-172 of human TXNDC12 (NP_056997.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TXNDC12

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Alternative Name: TXNDC12 (TXNDC12 Products)

Synonyms: AG1 antibody, AGR1 antibody, ERP16 antibody, ERP18 antibody, ERP19 antibody, PDIA16 antibody, TLP19 antibody, hAG-1 antibody, hTLP19 antibody, 0610040B21Rik antibody, ERp16 antibody, ERp19 antibody, RGD1305960 antibody, thioredoxin domain containing 12 antibody, thioredoxin domain containing 12 (endoplasmic reticulum) antibody, TXNDC12 antibody, Txndc12 antibody

Background: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.,TXNDC12,AG1,AGR1,ERP16,ERP18,ERP19,PDIA16,TLP19,hAG-1,hTLP19,Signal Transduction,TXNDC12

Molecular Weight: 19kDa

Gene ID: 51060

UniProt: O95881

Pathways: Cell RedoxHomeostasis