THEM4 antibody (AA 37-150)

Catalog No. ABIN7270796

Product Details anti-THEM4 Antibody

Target: THEM4 (Thioesterase Superfamily Member 4 (THEM4))

Binding Specificity: AA 37-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: THEM4 Rabbit pAb

Sequence: SSEEVILKDC SVPNPSWNKD LRLLFDQFMK KCEDGSWKRL PSYKRTPTEW IQDFKTHFLD PKLMKEEQMS QAQLFTRSFD DGLGFEYVMF YNDIEKRMVC LFQGGPYLEG PPGF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 37-150 of human THEM4 (NP_444283.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for THEM4

Target: THEM4 (Thioesterase Superfamily Member 4 (THEM4))

Alternative Name: THEM4 (THEM4 Products)

Background: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.,THEM4,CTMP,Signal Transduction,Kinase,PI3K-Akt Signaling Pathway,Immunology & Inflammation,THEM4

Molecular Weight: 27kDa

Gene ID: 117145

UniProt: Q5T1C6

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway