TCTN1 antibody (AA 130-310)

Catalog No. ABIN7270757

Product Details anti-TCTN1 Antibody

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Binding Specificity: AA 130-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: TCTN1 Rabbit pAb

Sequence: NFTANPPQRV FELVDQINPS IFCIHITNYK PALSFINPEV PDENNFDTLM KTSDGFTLNA ESYVSFTTKL DIPTAAKYEY GVPLQTSDSF LRFPSSLTSS LCTDNNPAAF LVNQAVKCTR KINLEQCEEI EALSMAFYSS PEILRVPDSR KKVPITVQSI VIQSLNKTLT RREDTDVLQP T

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human TCTN1 (NP_001076006.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCTN1

Target: TCTN1 (Tectonic Family Member 1 (TCTN1))

Alternative Name: TCTN1 (TCTN1 Products)

Background: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.,TCTN1,JBTS13,TECT1,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,TCTN1

Molecular Weight: 28kDa/52kDa/58kDa/61kDa/63kDa/64kDa

Gene ID: 79600

UniProt: Q2MV58

Pathways: Tube Formation