STEAP4 antibody (AA 1-100)

Catalog No. ABIN7270588

Product Details anti-STEAP4 Antibody

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: STEAP4 Rabbit pAb

Sequence: MEKTCIDALP LTMNSSEKQE TVCIFGTGDF GRSLGLKMLQ CGYSVVFGSR NPQKTTLLPS GAEVLSYSEA AKKSGIIIIA IHREHYDFLT ELTEVLNGKI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STEAP4 (NP_001192245).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Alternative Name: STEAP4 (STEAP4 Products)

Synonyms: STAMP2 antibody, TIARP antibody, TNFAIP9 antibody, MGC68826 antibody, STEAP4 antibody, MGC108044 antibody, steap4 antibody, 1110021O17Rik antibody, AI481214 antibody, Tiarp antibody, Tnfaip9 antibody, si:dkey-53p21.1 antibody, zgc:112143 antibody, STEAP4 metalloreductase antibody, STEAP4 metalloreductase L homeolog antibody, metalloreductase STEAP4 antibody, STEAP family member 4 antibody, STEAP4 antibody, steap4.L antibody, Steap4 antibody, steap4 antibody, LOC100136336 antibody, LOC100353852 antibody

Background: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011],STAMP2,SchLAH,TIARP,TNFAIP9,STEAP4,Cancer,Tumor immunology,Tumor-associated antigens,Tumor biomarkers,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,STEAP4

Molecular Weight: 31kDa/51kDa

Gene ID: 79689

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis