SPRED1 antibody (AA 120-320)

Catalog No. ABIN7270557

Product Details anti-SPRED1 Antibody

Target: SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

Binding Specificity: AA 120-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRED1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SPRED1 Rabbit pAb

Sequence: IEDISQGCPE SKNEAEGADD LQANEEDSSS SLVKDHLFQQ ETVVTSEPYR SSNIRPSPFE DLNARRVYMQ SQANQITFGQ PGLDIQSRSM EYVQRQISKE CGSLKSQNRV PLKSIRHVSF QDEDEIVRIN PRDILIRRYA DYRHPDMWKN DLERDDADSS IQFSKPDSKK SDYLYSCGDE TKLSSPKDSV VFKTQPSSLK I

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human SPRED1 (NP_689807.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPRED1

Target: SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

Alternative Name: SPRED1 (SPRED1 Products)

Background: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).,SPRED1,NFLS,PPP1R147,hSpred1,spred-1,Signal Transduction,G protein signaling,Signal Transduction,Kinase,MAPK-Erk Signaling Pathway,SPRED1

Molecular Weight: 50kDa

Gene ID: 161742

UniProt: Q7Z699

Pathways: Positive Regulation of Response to DNA Damage Stimulus