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SF3B1 antibody

SF3B1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7270542
  • Target See all SF3B1 Antibodies
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    Reactivity
    • 51
    • 35
    • 29
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 62
    • 4
    Rabbit
    Clonality
    • 48
    • 18
    Monoclonal
    Conjugate
    • 37
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3B1 antibody is un-conjugated
    Application
    • 53
    • 20
    • 20
    • 15
    • 13
    • 13
    • 11
    • 6
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purpose
    SF3B1 Rabbit mAb
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human SF3B1
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    Alternative Name
    SF3B1 (SF3B1 Products)
    Background
    This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155,Epigenetics & Nuclear Signaling,Protein phosphorylation,RNA Binding,SF3B1
    Molecular Weight
    155kDa
    Gene ID
    23451
    UniProt
    O75533
    Pathways
    Chromatin Binding
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