KCC2 antibody (AA 945-1025)

Catalog No. ABIN7270396

This Rabbit Polyclonal antibody specifically detects KCC2 in WB. It exhibits reactivity toward Human.

Quick Overview for KCC2 antibody (AA 945-1025) (ABIN7270396)

Target: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCC2 Antibody

Binding Specificity: AA 945-1025

Purpose: SLC12A5 Rabbit pAb

Sequence: TKNEREREIQ SITDESRGSI RRKNPANTRL RLNVPEETAG DSEEKPEEEV QLIHDQSAPS CPSSSPSPGE EPEGEGETDP E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 945-1025 of human SLC12A5 (NP_001128243.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KCC2

Target: KCC2 (SLC12A5) (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))

Alternative Name: SLC12A5

Background: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.,SLC12A5,EIEE34,EIG14,KCC2,hKCC2,Neuroscience,SLC12A5

Molecular Weight: 123kDa/126kDa

Gene ID: 57468

UniProt: Q9H2X9