SNW1 antibody (AA 300-536)

Catalog No. ABIN7270386

Product Details anti-SNW1 Antibody

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Binding Specificity: AA 300-536

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNW1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Purpose: SNW1 Rabbit pAb

Sequence: EAVEMRAQVE RKMAQKEKEK HEEKLREMAQ KARERRAGIK THVEKEDGEA RERDEIRHDR RKERQHDRNL SRAAPDKRSK LQRNENRDIS EVIALGVPNP RTSNEVQYDQ RLFNQSKGMD SGFAGGEDEI YNVYDQAWRG GKDMAQSIYR PSKNLDKDMY GDDLEARIKT NRFVPDKEFS GSDRRQRGRE GPVQFEEDPF GLDKFLEEAK QHGGSKRPSD SSRPKEHEHE GKKRRKE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-536 of human SNW1 (NP_036377.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Alternative Name: SNW1 (SNW1 Products)

Background: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.,SNW1,Bx42,NCOA-62,PRPF45,Prp45,SKIIP,SKIP,FUN20,SKIP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,SNW1

Molecular Weight: 61kDa

Gene ID: 22938

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway