SMAD6 antibody (AA 257-496)

Catalog No. ABIN7270355

Product Details anti-SMAD6 Antibody

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Binding Specificity: AA 257-496

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Smad6 Rabbit pAb

Sequence: PTVCCNPYHF SRLCGPESPP PPYSRLSPRD EYKPLDLSDS TLSYTETEAT NSLITAPGEF SDASMSPDAT KPSHWCSVAY WEHRTRVGRL YAVYDQAVSI FYDLPQGSGF CLGQLNLEQR SESVRRTRSK IGFGILLSKE PDGVWAYNRG EHPIFVNSPT LDAPGGRALV VRKVPPGYSI KVFDFERSGL QHAPEPDAAD GPYDPNSVRI SFAKGWGPCY SRQFITSCPC WLEILLNNPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6 (NP_005576.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMAD6

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Alternative Name: SMAD6 (SMAD6 Products)

Synonyms: madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody

Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.,SMAD6,AOVD2,HsT17432,MADH6,MADH7,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Hypertrophy,SMADs,SMAD6

Molecular Weight: 26kDa/35kDa/53kDa

Gene ID: 4091

UniProt: O43541

Pathways: Chromatin Binding