SETD4 antibody (AA 210-300)

Catalog No. ABIN7270264

Product Details anti-SETD4 Antibody

Target: SETD4 (SET Domain Containing 4 (SETD4))

Binding Specificity: AA 210-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SETD4 Rabbit pAb

Sequence: YLRPRQRECL SAEPDTCALA PYLDLLNHSP HVQVKAAFNE ETHSYEIRTT SRWRKHEEVF ICYGPHDNQR LFLEYGFVSV HNPHACVYVS R

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human SETD4 (NP_001007260).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SETD4

Target: SETD4 (SET Domain Containing 4 (SETD4))

Alternative Name: SETD4 (SETD4 Products)

Synonyms: MGC53706 antibody, dZ63M10.4 antibody, zgc:112252 antibody, C21orf18 antibody, C21orf27 antibody, AY037804 antibody, ORF21 antibody, Rda279 antibody, SET domain containing 4 L homeolog antibody, SET domain containing 4 antibody, setd4.L antibody, SETD4 antibody, setd4 antibody, Setd4 antibody

Background: Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively, leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3, thereby promoting heterochromatin formation. Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs (By similarity.,C21orf18,C21orf27,SETD4,Epigenetics & Nuclear Signaling,SETD4

Gene ID: 54093

UniProt: Q9NVD3