Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SRRT antibody (AA 623-872)

SRRT Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7270253
  • Target See all SRRT Antibodies
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    Binding Specificity
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 623-872
    Reactivity
    • 25
    • 7
    • 5
    • 1
    Human
    Host
    • 23
    • 2
    • 1
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This SRRT antibody is un-conjugated
    Application
    • 23
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purpose
    SRRT Rabbit pAb
    Sequence
    DYYNTCEYPN EDEMPNRCGI IHVRGPMPPN RISHGEVLEW QKTFEEKLTP LLSVRESLSE EEAQKMGRKD PEQEVEKFVT SNTQELGKDK WLCPLSGKKF KGPEFVRKHI FNKHAEKIEE VKKEVAFFNN FLTDAKRPAL PEIKPAQPPG PAQSLTPGLP YPHQTPQGLM PYGQPRPPIL GYGAGAVRPA VPTGGPPYPH APYGAGRGNY DAFRGQGGYP GKPRNRMVRG DPRAIVEYRD LDAPDDVDFF
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 623-872 of human SRRT (NP_001122325.1).
    Isotype
    IgG
    Top Product
    Discover our top product SRRT Primary Antibody
  • Application Notes
    IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    Alternative Name
    SRRT (SRRT Products)
    Synonyms
    CG7843 antibody, Dmel\\CG7843 antibody, anon-WO0118547.166 antibody, ars2 antibody, ars2-A antibody, serrate antibody, ARS2 antibody, ASR2 antibody, 2810019G02Rik antibody, ASR2A antibody, ASR2B antibody, ASR2C antibody, ASR2D antibody, Ars2 antibody, Asr2 antibody, MGC92060 antibody, CHUNP6881 antibody, zgc:92060 antibody, Arsenic resistance protein 2 antibody, serrate, RNA effector molecule S homeolog antibody, serrate, RNA effector molecule antibody, serrate RNA effector molecule homolog (Arabidopsis) antibody, Ars2 antibody, srrt.S antibody, SRRT antibody, Srrt antibody, srrt antibody
    Background
    Acts as a mediator between the cap-binding complex (CBC and the primary microRNAs (miRNAs processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi by miRNAs. Binds capped RNAs (m7GpppG-capped RNA, however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity.,SRRT,ARS2,ASR2,serrate,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,SRRT
    Molecular Weight
    96kDa/100kDa
    Gene ID
    51593
    UniProt
    Q9BXP5
    Pathways
    Notch Signaling, Stem Cell Maintenance
You are here:
Support