RUSC1 antibody (AA 1-320)

Catalog No. ABIN7270114

Product Details anti-RUSC1 Antibody

Target: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Binding Specificity: AA 1-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUSC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: RUSC1 Rabbit pAb

Sequence: MAEAQSGTGQ LQEQKKGLLI AVSVSVDKII SHFGAARNLV QKAQLGDSRL SPDVGHLVLT TLCPALHALV ADGLKPFRKD LITGQRRSSP WSVVEASVKP GSSTRSLGTL YSQVSRLAPL SSSRSRFHAF ILGLLNTKQL ELWFSSLQED AGLLSLLYLP TGFFSLARGG CPSLSTELLL LLQPLSVLTF HLDLLFEHHH HLPLGPPQAP APPGPPPALQ QTMQAMLHFG GRLAQSLRGT SKEAASDPSD SPNLPTPGSW WEQLTQASRV YASGGTEGFP LSRWAPGRHG TAAEEGAQER PLPTDEMAPG RGLWLGRLFG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human RUSC1 (NP_055143.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RUSC1

Target: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Alternative Name: RUSC1 (RUSC1 Products)

Background: Associates with the adapter-like complex 4 (AP-4 and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. Signaling adapter which plays a role in neuronal differentiation. Involved in regulation of NGF-dependent neurite outgrowth. May play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins (By similarity. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.,RUSC1,NESCA,Signal Transduction,Neuroscience,RUSC1

Molecular Weight: 46kDa/52kDa/85kDa/96kDa

Gene ID: 23623

UniProt: Q9BVN2