A930029B02Rik antibody, rnf152-a antibody, ring finger protein 152 antibody, ring finger protein 152 S homeolog antibody, RNF152 antibody, Rnf152 antibody, rnf152.S antibody
Background
E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed.,RNF152,RNF152