Raptor antibody

Catalog No. ABIN7269900

Product Details anti-Raptor Antibody

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Raptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: Raptor Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Raptor

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Raptor

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Alternative Name: RPTOR (RPTOR Products)

Synonyms: KOG1 antibody, Mip1 antibody, 4932417H02Rik antibody, Rap antibody, Raptor antibody, mKIAA1303 antibody, RGD1311784 antibody, raptor antibody, regulatory associated protein of MTOR complex 1 antibody, regulatory associated protein of MTOR, complex 1 antibody, regulatory associated protein of MTOR, complex 1 L homeolog antibody, RPTOR antibody, Rptor antibody, rptor.L antibody, rptor antibody

Background: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],KOG1, Mip1,AMPK Signaling Pathway,Autophagy,Autophagy_Regulator,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Insulin Receptor Signaling Pathway,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,T Cell Receptor Signaling Pathway,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,RPTOR

Molecular Weight: 149kDa

Gene ID: 57521

UniProt: Q8N122

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, Warburg Effect