CALDAG-GEFI antibody, CDC25L antibody, xrasgrp2 antibody, RASGRP2 antibody, Caldaggef1 antibody, CalDAG-GEFI antibody, rasgrp2 antibody, RAS guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antibody, RAS, guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antibody, RASGRP2 antibody, rasgrp2.S antibody, Rasgrp2 antibody, rasgrp2.L antibody
Background
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.,RASGRP2,CALDAG-GEFI,CDC25L,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,RASGRP2