PKM2 antibody
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- Target See all PKM2 Antibodies
- PKM2 (Pyruvate Kinase M2 (PKM2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PKM2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- PKM2-specific Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of Human PKM2.
- Isotype
- IgG
- Top Product
- Discover our top product PKM2 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PKM2 (Pyruvate Kinase M2 (PKM2))
- Alternative Name
- PKM2 (PKM2 Products)
- Background
- This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011],CTHBP,HEL-S-30,OIP3,PK3,PKM2,TCB,THBP1,PKM,Cancer,Carbohydrate metabolism,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Protein phosphorylation,RNA Binding,Signal Transduction,Tumor biomarkers,Warburg Effect,PKM2
- Molecular Weight
- 58kDa
- Gene ID
- 5315
- UniProt
- P14618
- Pathways
- Warburg Effect
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