PROZ antibody (AA 220-340)

Catalog No. ABIN7269713

Product Details anti-PROZ Antibody

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Binding Specificity: AA 220-340

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROZ antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PROZ Rabbit pAb

Sequence: SLLHRNITVK TYFNRTSQDP LMIKITHVHV HMRYDADAGE NDLSLLELEW PIQCPGAGLP VCTPEKDFAE HLLIPRTRGL LSGWARNGTD LGNSLTTRPV TLVEGEECGQ VLNVTVTTRT Y

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PROZ

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Alternative Name: PROZ (PROZ Products)

Synonyms: PZ antibody, 1300015B06Rik antibody, betaH1 antibody, protein Z, vitamin K dependent plasma glycoprotein antibody, protein Z, vitamin K-dependent plasma glycoprotein antibody, protein Z, vitamin K-dependent plasma glycoprotein b antibody, hemoglobin Z, beta-like embryonic chain antibody, PROZ antibody, Proz antibody, prozb antibody, Hbb-bh1 antibody

Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.,PROZ,PZ,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Blood,Coagulation,Serum Proteins,PROZ

Molecular Weight: 44kDa/47kDa

Gene ID: 8858

UniProt: P22891