QAELHPLPQL KDATSNEQQE LFCQKLQQCC ILFDFMDSVS DLKSKEIKRA TLNELVEYVS TNRGVIVESA YSDIVKMISA N
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human PP2A-B56alpha/PR61A/PP2A-B56alpha/PR61A/PPP2R5A (NP_006234.1).
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.,PPP2R5A,B56A,PR61A,B56alpha,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Neuroscience,PPP2R5A