PDIR antibody, PDIA5 antibody, sb:cb441 antibody, wu:fb98h09 antibody, zgc:172235 antibody, 2700053F16Rik antibody, AU015525 antibody, Pdir antibody, protein disulfide isomerase family A member 5 antibody, protein disulfide isomerase family A, member 5 antibody, microRNA 7110 antibody, protein disulfide isomerase associated 5 antibody, PDIA5 antibody, Pdia5 antibody, MIR7110 antibody, pdia5 antibody
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.,PDIA5,PDIR,Cell Biology & Developmental Biology,PDIA5