PDCD10 antibody (AA 1-212)

Catalog No. ABIN7269539

Product Details anti-PDCD10 Antibody

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Binding Specificity: AA 1-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: [KO Validated] PDCD10 Rabbit pAb

Sequence: MRMTMEEMKN EAETTSMVSM PLYAVMYPVF NELERVNLSA AQTLRAAFIK AEKENPGLTQ DIIMKILEKK SVEVNFTESL LRMAADDVEE YMIERPEPEF QDLNEKARAL KQILSKIPDE INDRVRFLQT IKDIASAIKE LLDTVNNVFK KYQYQNRRAL EHQKKEFVKY SKSFSDTLKT YFKDGKAINV FVSANRLIHQ TNLILQTFKT VA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Grade: KO Validated

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDCD10

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Alternative Name: PDCD10 (PDCD10 Products)

Synonyms: CCM3 antibody, TFAR15 antibody, 2410003B13Rik antibody, Ccm3 antibody, Tfa15 antibody, Tfar15 antibody, zgc:85629 antibody, ccm3a antibody, pdcd10 antibody, zgc:65826 antibody, programmed cell death 10 antibody, programmed cell death 10 S homeolog antibody, programmed cell death 10b antibody, programmed cell death 10a antibody, PDCD10 antibody, Pdcd10 antibody, pdcd10.S antibody, pdcd10b antibody, pdcd10a antibody

Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.,PDCD10,CCM3,TFAR15,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Cardiovascular,Angiogenesis,PDCD10

Molecular Weight: 24kDa

Gene ID: 11235

UniProt: Q9BUL8