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PRAME antibody (AA 1-200)

PRAME Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7269507
  • Target See all PRAME Antibodies
    PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
    Binding Specificity
    • 16
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1-200
    Reactivity
    • 50
    • 20
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 48
    • 2
    Rabbit
    Clonality
    • 50
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRAME antibody is un-conjugated
    Application
    • 23
    • 16
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    PRAME Rabbit pAb
    Sequence
    MERRRLWGSI QSRYISMSVW TSPRRLVELA GQSLLKDEAL AIAALELLPR ELFPPLFMAA FDGRHSQTLK AMVQAWPFTC LPLGVLMKGQ HLHLETFKAV LDGLDVLLAQ EVRPRRWKLQ VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRAME (NP_006106.1).
    Isotype
    IgG
    Top Product
    Discover our top product PRAME Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
    Alternative Name
    PRAME (PRAME Products)
    Synonyms
    PRAME antibody, CT130 antibody, MAPE antibody, OIP-4 antibody, OIP4 antibody, 4930534P07Rik antibody, preferentially expressed antigen in melanoma antibody, PRAME antibody, Prame antibody
    Background
    This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.,PRAME,CT130,MAPE,OIP-4,OIP4,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor biomarkers,PRAME
    Molecular Weight
    57kDa
    Gene ID
    23532
    UniProt
    P78395
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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