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PHKA1 antibody (AA 600-820)

PHKA1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7269367
  • Target See all PHKA1 Antibodies
    PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))
    Binding Specificity
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-820
    Reactivity
    • 17
    • 2
    • 2
    • 1
    Human
    Host
    • 16
    • 2
    • 1
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHKA1 antibody is un-conjugated
    Application
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    PHKA1 Rabbit pAb
    Sequence
    QTGKLSEFLT TSCCTHLSFM DPGPEGKLYS EDYDDNYDYL ESGNWMNDYD STSHARCGDE VARYLDHLLA HTAPHPKLAP TSQKGGLDRF QAAVQTTCDL MSLVTKAKEL HVQNVHMYLP TKLFQASRPS FNLLDSPHPR QENQVPSVRV EIHLPRDQSG EVDFKALVLQ LKETSSLQEQ ADILYMLYTM KGPDWNTELY NERSATVREL LTELYGKVGE I
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human PHKA1 (NP_001116142.1).
    Isotype
    IgG
    Top Product
    Discover our top product PHKA1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))
    Alternative Name
    PHKA1 (PHKA1 Products)
    Synonyms
    PHKA1 antibody, wu:fl37h01 antibody, 5330411D17 antibody, 9830108K24Rik antibody, Phka antibody, Pcyt1b antibody, PHKA antibody, phosphorylase kinase regulatory subunit alpha 1 antibody, phosphorylase kinase, alpha 1a (muscle) antibody, phosphorylase kinase, alpha 1 (muscle) antibody, phosphorylase kinase alpha 1 antibody, PHKA1 antibody, phka1a antibody, phka1 antibody, Phka1 antibody
    Background
    Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.,PHKA1,PHKA,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Calcium Signaling,PHKA1
    Molecular Weight
    129kDa/135kDa/137kDa
    Gene ID
    5255
    UniProt
    P46020
    Pathways
    Cellular Glucan Metabolic Process
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