PGA3 antibody (AA 63-180)

Catalog No. ABIN7269204

Product Details anti-PGA3 Antibody

Target: PGA3 (Pepsinogen 3, Group I (Pepsinogen A) (PGA3))

Binding Specificity: AA 63-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGA3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PGA3 Rabbit pAb

Sequence: VDEQPLENYL DMEYFGTIGI GTPAQDFTVV FDTGSSNLWV PSVYCSSLAC TNHNRFNPED SSTYQSTSET VSITYGTGSM TGILGYDTVQ VGGISDTNQI FGLSETEPGS FLYYAPFD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA3 (NP_001073275.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PGA3

Target: PGA3 (Pepsinogen 3, Group I (Pepsinogen A) (PGA3))

Alternative Name: PGA3 (PGA3 Products)

Synonyms: PGA4 antibody, PGA5 antibody, pepsinogen 3, group I (pepsinogen A) antibody, PGA3 antibody

Background: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.,PGA3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,PGA3

Molecular Weight: 41kDa

Gene ID: 643834

UniProt: P0DJD8