PSIP1 antibody (AA 301-530)

Catalog No. ABIN7269192

Product Details anti-PSIP1 Antibody

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Binding Specificity: AA 301-530

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PSIP1 Rabbit pAb

Sequence: NMLKGQHEKE AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK NSLKIDNLDV NRCIEALDEL ASLQVTMQQA QKHTEMITTL KKIRRFKVSQ VIMEKSTMLY NKFKNMFLVG EGDSVITQVL NKSLAEQRQH EEANKTKDQG KKGPNKKLEK EQTGSKTLNG GSDAQDGNQP QHNGESNEDS KDNHEASTKK KPSSEERETE ISLKDSTLDN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1 (PSIP1 Products)

Background: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.,PSIP1,DFS70,LEDGF,PAIP,PSIP2,p52,p75,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Stem Cells,PSIP1

Molecular Weight: 37kDa/60kDa

Gene ID: 11168

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization