PAK3 antibody

Catalog No. ABIN7269161

Product Details anti-PAK3 Antibody

Target: PAK3

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PAK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: PAK3 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PAK3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAK3

Target: PAK3

Alternative Name: PAK3 (PAK3 Products)

Synonyms: CDKN1A antibody, MRX30 antibody, MRX47 antibody, OPHN3 antibody, PAK3beta antibody, bPAK antibody, hPAK3 antibody, PAK-3 antibody, Pak65alpha antibody, Pak65beta antibody, Stk4 antibody, beta-PAK antibody, XPak3 antibody, bpak antibody, cdkn1a antibody, mrx30 antibody, mrx47 antibody, ophn3 antibody, pak3 antibody, pak3-A antibody, pak3beta antibody, p21 (RAC1) activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 antibody, p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog antibody, PAK3 antibody, Pak3 antibody, pak3.L antibody

Background: The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Apr 2016],ARA, MRX30, MRX47, OPHN3, PAK-3, PAK3beta, bPAK, beta-PAK,Cell Biology & Developmental Biology,Cytoskeleton_Microtubules,G protein signaling,G protein signaling_Small G proteins,Kinase,Kinase_Serine/threonine kinases,MAPK-Erk Signaling Pathway,Neuroscience,Signal Transduction,TGF-b-Smad Signaling Pathway,PAK3

Molecular Weight: 62kDa

Gene ID: 5063

UniProt: O75914