PHOX2B antibody

Catalog No. ABIN7269159

Product Details anti-PHOX2B Antibody

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PHOX2B Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PHOX2B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B (PHOX2B Products)

Synonyms: phox2 antibody, xphox2b antibody, phox2b antibody, PHOX2B antibody, pmx2b antibody, nbphox antibody, NBLST2 antibody, NBPhox antibody, PMX2B antibody, Dilp1 antibody, Pmx2b antibody, paired-like homeobox 2b antibody, paired like homeobox 2b S homeolog antibody, paired-like homeobox 2bb antibody, paired like homeobox 2b antibody, phox2b antibody, phox2b.S antibody, phox2bb antibody, PHOX2B antibody, Phox2b antibody

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016],NBLST2, NBPhox, PMX2B,Epigenetics & Nuclear Signaling,Neuroscience,Signal Transduction,Transcription Factors,PHOX2B

Molecular Weight: 35kDa

Gene ID: 8929

UniProt: Q99453