OPN4 antibody (AA 365-489)

Catalog No. ABIN7269103

Product Details anti-OPN4 Antibody

Target: OPN4 (Opsin 4 (OPN4))

Binding Specificity: AA 365-489

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPN4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: OPN4 Rabbit pAb

Sequence: HPKYRVAIAQ HLPCLGVLLG VSRRHSRPYP SYRSTHRSTL TSHTSNLSWI SIRRRQESLG SESEVGWTHM EAAAVWGAAQ QANGRSLYGQ GLEDLEAKAP PRPQGHEAET PGKTKGLIPS QDPRM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OPN4

Target: OPN4 (Opsin 4 (OPN4))

Alternative Name: OPN4 (OPN4 Products)

Synonyms: MOP antibody, 1110007J02Rik antibody, Gm533 antibody, OPN4-2 antibody, cOpn4L antibody, melanopsin antibody, opn4-A antibody, Xmop antibody, opn4 antibody, opn4d antibody, opsin 4 antibody, opsin 4 (melanopsin) antibody, melanopsin antibody, melanopsin-B-like L homeolog antibody, opsin 4a (melanopsin) antibody, OPN4 antibody, Opn4 antibody, LOC100303707 antibody, LOC100485437.L antibody, opn4a antibody

Background: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,OPN4,MOP,opsin 4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,OPN4

Molecular Weight: 52kDa/53kDa

Gene ID: 94233

UniProt: Q9UHM6