NCOA4 antibody (AA 495-614)

Catalog No. ABIN7269007

Product Details anti-NCOA4 Antibody

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Binding Specificity: AA 495-614

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: NCOA4 Rabbit pAb

Sequence: SEWLIRPPYK EGSPKEVPGT EDRAGKQKFK SPMNTSWCSF NTADWVLPGK KMGNLSQLSS GEDKWLLRKK AQEVLLNSPL QEEHNFPPDH YGLPAVCDLF ACMQLKVDKE KWLYRTPLQM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 495-614 of human NCOA4 (NP_005428.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: NCOA4 (NCOA4 Products)

Synonyms: zgc:55307 antibody, zgc:77270 antibody, NCOA4 antibody, MGC138109 antibody, rfg antibody, ele1 antibody, ptc3 antibody, ara70 antibody, MGC84996 antibody, DKFZp469A035 antibody, DKFZp459B2429 antibody, DKFZp469A1925 antibody, ncoa4 antibody, ARA70 antibody, ELE1 antibody, PTC3 antibody, RFG antibody, 1110034E15Rik antibody, 4432406M01Rik antibody, AI227008 antibody, Rfg antibody, nuclear receptor coactivator 4 antibody, nuclear receptor coactivator 4 S homeolog antibody, Ncoa4 antibody, ncoa4 antibody, NCOA4 antibody, ncoa4.S antibody

Background: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.,NCOA4,ARA70,ELE1,PTC3,RFG,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,NCOA4

Molecular Weight: 32kDa/69kDa/71kDa/73kDa

Gene ID: 8031

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway