MYST3 antibody (AA 800-1000)

Catalog No. ABIN7268768

Product Details anti-MYST3 Antibody

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Binding Specificity: AA 800-1000

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: KAT6A Rabbit pAb

Sequence: EEPQCQEREL EISVGKSVSH ENKEQDSYSV ESEKKPEVMA PVSSTRLSKQ VLPHDSLPAN SQPSRRGRWG RKNRKTQERF GDKDSKLLLE ETSSAPQEQY GECGEKSEAT QEQYTESEEQ LVASEEQPSQ DGKPDLPKRR LSEGVEPWRG QLKKSPEALK CRLTEGSERL PRRYSEGDRA VLRGFSESSE EEEEPESPRS S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human KAT6A (NP_001092883.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MYST3

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Alternative Name: KAT6A (MYST3 Products)

Synonyms: bmd antibody, moz antibody, myst3 antibody, DKFZp469B0815 antibody, MOZ antibody, MYST3 antibody, RUNXBP2 antibody, ZC2HC6A antibody, ZNF220 antibody, 1500036M03 antibody, 9930021N24Rik antibody, Myst3 antibody, Zfp220 antibody, Moz antibody, Runxbp2 antibody, Znf220 antibody, K(lysine) acetyltransferase 6A antibody, lysine acetyltransferase 6A antibody, kat6a antibody, KAT6A antibody, Kat6a antibody

Background: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.,KAT6A,MOZ,MRD32,MYST-3,MYST3,RUNXBP2,ZC2HC6A,ZNF220,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6A

Molecular Weight: 225kDa

Gene ID: 7994

UniProt: Q92794

Pathways: Stem Cell Maintenance, Embryonic Body Morphogenesis